منابع مشابه
Radiocontrast induced nephropathy.
In spite of improvements in chemical structure, contrast media assisted X-ray examination is still the third leading cause of hospital-acquired acute renal failure. An increase >50% or >88 micro mol/L in S-creatinine is a clinically important acute renal failure. The peak in S-creatinine occurs within 2-5 days after exposure. The frequency of oliguria, transient or permanent haemodialysis is un...
متن کاملA primer in radiocontrast-induced nephropathy.
Despite recent medical progress in supportive medical absent, DM present (n=318); (iii) RI present, DM absent (n=298); (iv) both RI and DM present (n=216) therapy, the frequency of hospital-acquired acute renal failure has increased in recent years from ~5% to [14]. The frequency of RCIN, defined as an increase of serum creatinine 0.5 mg/dl, was 8.5% for iohexol (I ) 6.4% [1,2]. Even more distr...
متن کاملThe prevention of radiocontrast-agent-induced nephropathy by hemofiltration.
BACKGROUND Nephropathy induced by exposure to radiocontrast agents, a possible complication of percutaneous coronary interventions, is associated with significant in-hospital and long-term morbidity and mortality. Patients with preexisting renal failure are at particularly high risk. We investigated the role of hemofiltration, as compared with isotonic-saline hydration, in preventing contrast-a...
متن کاملalpha2-Adrenergic agonists protect against radiocontrast-induced nephropathy in mice.
Radiocontrast nephropathy (RCN) is a common clinical problem for which there is no effective therapy. Utilizing a murine model, we tested the hypothesis that alpha(2)-adrenergic receptor agonists (clonidine and dexmedetomidine) protect against RCN induced with iohexol (a nonionic low-osmolar radiocontrast). C57BL/6 mice were pretreated with saline, clonidine, or dexmedetomidine before induction...
متن کاملN-acetylcysteine in the prevention of radiocontrast-induced nephropathy.
N-acetylcysteine is a remarkably active agent shown to be useful in a variety of clinical settings. The drug has actions relevant to radiocontrast-induced nephropathy (RCIN) that include vasodilatation, enhancement of renal medullary blood flow, and antioxidant properties. The drug's pharmacokinetics are remarkable for almost complete first pass metabolism after oral administration, resulting i...
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ژورنال
عنوان ژورنال: European Journal of Vascular and Endovascular Surgery
سال: 2003
ISSN: 1078-5884
DOI: 10.1053/ejvs.2002.1824