RAD51 Mutants Cause Replication Defects and Chromosomal Instability
نویسندگان
چکیده
منابع مشابه
Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
BACKGROUND Despite our substantial understanding of molecular mechanisms and gene mutations involved in cancer, the technical approaches for diagnosis and prognosis of cancer are limited. In routine clinical diagnosis of cancer, the procedure is very basic: nuclear morphology is used as a common assessment of the degree of malignancy, and hence acts as a prognostic and predictive indicator of t...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2012
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.00406-12