Quorum quenching: role in nature and applied developments

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Quorum quenching: role in nature and applied developments.

Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density and regulate gene expression accordingly: the QS-regulated processes deal with multicellular behaviors (e.g. growth and development of biofilm), horizontal gene transfer and host-microbe (symbiosis and pathogenesis) and microbe-microbe interactions. QS signaling requires the synthesis, exchange and percep...

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Bacteria have the remarkable ability to communicate as a group in what has become known as quorum sensing (QS), and this trait has been associated with important bacterial phenotypes, such as virulence and biofilm formation. Bacteria also have an incredible ability to evolve resistance to all known antimicrobials. Hence, although inhibition of QS has been hailed as a means to reduce virulence i...

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ژورنال

عنوان ژورنال: FEMS Microbiology Reviews

سال: 2015

ISSN: 1574-6976

DOI: 10.1093/femsre/fuv038