Quaternary structure ofEscherichia colipolynucleotide phosphorylase: new evidence for a trimeric structure

Trimeric Structure of

Trimeric Structure of Langerin*

Langerin, an endocytic receptor of Langerhans cells, binds pathogens such as human immunodeficiency virus by recognition of surface glycoconjugates and mediates their internalization into Birbeck granules. Langerin has an extracellular region consisting of a C-type carbohydrate-recognition domain (CRD) and a neck region that stabilizes formation of trimers. As in many other C-type lectins, olig...

A trimeric quaternary structure is conserved in bacterial and human glutamate transporters.

Neuronal and glial glutamate transporters play a central role in the termination of synaptic transmission and in extracellular glutamate homeostasis in the mammalian central nervous system. They are known to be multimers; however, the number of subunits forming a functional transporter is controversial. We studied the subunit stoichiometry of two distantly related glutamate transporters, the hu...

Prediction of quaternary structure from primary structure

MOTIVATION The 'sequence implies conformation' principle has been the motivation for the construction of numerous systems of secondary and tertiary structure prediction. Computational experiments have shown that this principle can now be extended to quaternary structure prediction. This work appears to be the first effort to predict quaternary structure properties from sequence. RESULTS The s...

DESIGN AND STRUCTURE OF A NEW DEVICE FOR AUDITORY ELECTRICAL STIMULATION FOR SUPPRESSION OF TINNITUS

Auditory Electrical Stimulation for Tinnitus Suppression Tinnitus is the conscious experience of sound which arises in the head of its owner, but without a voluntary origin obvious to that person. About 10-15% of all adults report prolonged spontaneous tinnitus (PST). There are a lot of methods for suppressing this complaint. One of these methods is electrical stimulation. Electrical stimu...