Quasimonomorphic Mononucleotide Repeats for High-Level Microsatellite Instability Analysis
نویسندگان
چکیده
منابع مشابه
Quasimonomorphic Mononucleotide Repeats for High-Level Microsatellite Instability Analysis
Microsatellite instability (MSI) analysis is becoming more and more important to detect sporadic primary tumors of the MSI phenotype as well as in helping to determine Hereditary Non-Polyposis Colorectal Cancer (HNPCC) cases. After some years of conflicting data due to the absence of consensus markers for the MSI phenotype, a meeting held in Bethesda to clarify the situation proposed a set of 5...
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MSI analysis is becoming increasingly important for the detection of both hereditary non-polyposis colorectal cancer and sporadic primary colorectal tumours with MSI high phenotype. The Bethesda panel of five microsatellite markers has been proposed to provide uniform criteria for MSI analysis. Here we report on an MSI analysis approach using quasimonomorphic mononucleotide repeats and denatura...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2004
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2004/159347