Quantitative Proteomic Analysis of Gingival Crevicular Fluid in Different Periodontal Conditions

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Quantitative Proteomic Analysis of Gingival Crevicular Fluid in Different Periodontal Conditions

AIM To quantify the proteome composition of the GCF in periodontal health (HH) and in sites with different clinical conditions in chronic periodontitis (CP) subjects. MATERIAL AND METHODS 5 subjects with HH and 5 with CP were submitted to full-mouth periodontal examination, and GCF sampling. Sites in the CP group were classified and sampled as periodontitis (P, probing depth, PD>4 mm), gingiv...

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Oral Fluid-Based Biomarkers in Periodontal Disease – Part 2. Gingival Crevicular Fluid

Periodontal diagnosis and treatment plan are based on the assessment of probing depth, clinical attachment level, plaque index, gingival index, bleeding on probing, suppuration, furcation involvement, mobility, and radiographic findings. However, these clinical parameters are not sufficiently sensitive and specific to identify disease activity in individual sites or to predict future attachment...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0075898