Quantitative modeling of laser speckle imaging
نویسندگان
چکیده
منابع مشابه
Quantitative modeling of laser speckle imaging.
We have analyzed the image formation and dynamic properties in laser speckle imaging (LSI) both experimentally and with Monte Carlo simulation. We show for the case of a liquid inclusion that the spatial resolution and the signal itself are both significantly affected by scattering from the turbid environment. Multiple scattering leads to blurring of the dynamic inhomogeneity as detected by LSI...
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Laser speckle flowmetry suffers from a debated quantification of the inverse relation between decorrelation time (τc) and blood flow velocity (V), i.e. 1/τc = αV. Using a modified microcirculation imager (integrated sidestream dark field - laser speckle contrast imaging [SDF-LSCI]), we experimentally investigate on the influence of the optical properties of scatterers on α in vitro and in vivo....
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The analysis of speckle contrast in a time-integrated speckle pattern enables visualization of superficial blood flow in exposed vasculature, a method we call laser speckle imaging (LSI). With current methods, LSI does not enable visualization of subsurface or small vasculature, because of optical scattering by stationary structures. In this work we propose a new technique called photothermal L...
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Laser speckle imaging (LSI) enables measurement of relative changes in blood flow in biological tissues. We postulate that a point-of-care form factor will lower barriers to routine clinical use of LSI. Here, we describe a first-generation handheld LSI device based on a tablet computer. The coefficient of variation of speckle contrast was <2% after averaging imaging data collected over an acqui...
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483 peripheral microcirculatory blood flow on a large area of the body.1 LSCI is user‐friendly and shows very good reproducibility as well as excellent spa‐ tial and temporal resolutions.2 In clinical studies, LSCI coupled with reactivity tests enable to esti‐ mate the endothelial and neurovascular function. We present the measurements of skin per‐ fusion assessed by LSCI in patients with pri‐ ...
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ژورنال
عنوان ژورنال: Optics Letters
سال: 2006
ISSN: 0146-9592,1539-4794
DOI: 10.1364/ol.31.003465