Quantitative measurement of amoxicillin in Ibuprofen tablets using UPLC

Quantitative Estimation of Naproxen in Tablets Using Ibuprofen Sodium as Hydrotropic Agent

In the present investigation 0.5 M ibuprofen sodium solution has been used as hydrotropic solubilizing agent for naproxen, a poorly water-soluble drug and in it there was more than 350 fold enhancement in the solubility of naproxen as compared to the solubility in distilled water. Therefore, this hydrotropic solution was employed to extract out the drug from its tablet dosage form for quantitat...

Amoxicillin/Clavulanate Potassium Tablets

DESCRIPTION Amoxicillin/clavulanate potassium is an oral antibacterial combination consisting of the semisynthetic antibiotic amoxicillin and the β-lactamase inhibitor, clavulanate potassium (the potassium salt of clavulanic acid). Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid. The amoxicillin molecular formula is C16H19N3O5S•3H2O, a...

Quality Evaluation of Traditional Chinese Medicine Compounds in Xiaoyan Lidan Tablets: Fingerprint and Quantitative Analysis Using UPLC-MS.

XiaoyanLidan tablets (XYLDTs) are traditional Chinese medicines frequently used for syndromes of the liver and gallbladder, cholecystitis and cholangitis. To evaluate the consistency of the quality of commercial XYLDT preparations, we established a simple and reliable ultra-performance liquid chromatography (UPLC) method with a photodiode array (PDA) detector and mass spectrometry (MS), includi...

Measurement and Correlation of Ibuprofen in Supercritical Carbon Dioxide Using Stryjek and Vera EOS

Esophageal ulcer induced by ibuprofen tablets

The Non-steroidal antiinflammatory drugs (NSAIDs) are one of the most widely prescribed drugs, commonly used for rheumatoid diseases and illnesses accompanied by pain. However, the use of NSAIDs is often limited by the gastrointestinal toxicity. The NSAIDs inhibit cyclooxygenase (COX), which is an enzyme in the prostaglandin synthetic pathway, thereby decreasing pain, fever, and inflammation. T...