Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
نویسندگان
چکیده
منابع مشابه
Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
Quantitative cross-linking/mass spectrometry (QCLMS) probes protein structural dynamics in solution by quantitatively comparing the yields of cross-links between different conformational statuses. We have used QCLMS to understand the final maturation step of the proteasome lid and also to elucidate the structure of complement C3(H2O). Here we benchmark our workflow using a structurally well-des...
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ژورنال
عنوان ژورنال: Wellcome Open Research
سال: 2016
ISSN: 2398-502X
DOI: 10.12688/wellcomeopenres.9896.1