Quantifying the heritability of task-related brain activation and performance during the N-back working memory task: A twin fMRI study
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چکیده
منابع مشابه
Quantifying the heritability of task-related brain activation and performance during the N-back working memory task: a twin fMRI study.
Working memory-related brain activation has been widely studied, and impaired activation patterns have been reported for several psychiatric disorders. We investigated whether variation in N-back working memory brain activation is genetically influenced in 60 pairs of twins, (29 monozygotic (MZ), 31 dizygotic (DZ); mean age 24.4+/-1.7S.D.). Task-related brain response (BOLD percent signal diffe...
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Methods: BOLD fMRI data were acquired during the 0-back and 2-back conditions of a spatial N-back working memory task (see Fig. 1 in [1]) in 366 twins on a 4T Bruker Medspec MRI scanner. Echo Planar Images of all twins were realigned, coregistered with the twin’s 3D T1-weighted scan, spatially normalised in MNI atlas space, smoothed with an 8 mm FWHM Gaussian kernel, and detrended, using SPM5. ...
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ژورنال
عنوان ژورنال: Biological Psychology
سال: 2008
ISSN: 0301-0511
DOI: 10.1016/j.biopsycho.2008.03.006