Quantifying intraocular scatter with near diffraction-limited double-pass point spread function

Interactive Point Spread Function Simulation with Diffraction and Interference Effects

Interactive simulation of point spread functions is an invaluable tool for evaluating optical designs. We present an interactive method for simulating the point spread function for designs that require diffraction and interference effects. These effects occure when the design contains apertures whose size approaches the wavelength of light, typically in the form of gratings or masks. Traditiona...

Measured double-pass intensity point-spread function after adaptive optics correction of ocular aberrations.

The double-pass intensity point-spread function was recorded in four subjects using a monochromatic source emitting at 543 nm, through a 6.7-mm diameter pupil i) at the fovea after adaptive optics correction of the ocular aberrations, ii) at the fovea without adaptive optics correction, and iii) at 2 degrees of eccentricity with adaptive optics correction. The half-width at half-maximum of the ...

Phase transfer and point-spread function of the human eye determined by a new asymmetric double-pass method.

A recent study has shown that the double-pass method provides a good estimate of the ocular modulation transfer function (MTF) but that it does not yield the phase transfer function (PTF) [J. Opt. Soc. Am. A 12, 195 (1995)]. Therefore, one cannot recover the true retinal point-spread function (PSF). We present a modification of the double-pass method to overcome this problem. The key is to brea...

Near-Diffraction-Limited Tunable Liquid Crystal Lens with Simplified Design

Three-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function.

We demonstrate single-molecule fluorescence imaging beyond the optical diffraction limit in 3 dimensions with a wide-field microscope that exhibits a double-helix point spread function (DH-PSF). The DH-PSF design features high and uniform Fisher information and has 2 dominant lobes in the image plane whose angular orientation rotates with the axial (z) position of the emitter. Single fluorescen...