Quantification of Doxycycline Hyclate in Different Pharmaceutical Samples by UV Assay
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Acid-base Titrimetric Assay of Hydroxyzine Dihydrochloride in Pharmaceutical Samples
Two simple titrimetric methods have been developed for the determination of hydroxyzine dihydrochloride (HDH) in pure form and in tablets. The principle of the methods are simple acid-base reactions in which the hydrochloride content of the drug was determined by titrating with an aqueous standardized NaOH solution either visually using phenolphthalein as indicator (method A) or potentiometrica...
متن کاملSensitive and selective spectrophotometric assay of doxycycline hyclate in pharmaceuticals using Folin-Ciocalteu reagent PAVAGADA JAGANNATHAMURTHY RAMESH
methylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride hemiethanol hemihydrate (Fig. 1), is one of the tetracycline derivatives, which has a wide range of antibacterial activities. DOX is frequently used to treat chronic prostatitis, sinusitis, syphilis, chlamydia, pelvic inflammatory disease, acne, rosacea, and rickettsia...
متن کاملAn approach to Improve Therapeutic Efficacy of Doxycycline Hyclate in Treatment of Periodontitis
A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...
متن کاملAn approach to Improve Therapeutic Efficacy of Doxycycline Hyclate in Treatment of Periodontitis
A number of ways have been investigated for administration of antibacterial agents in dealing of plaque-initiated periodontal disease. These include prolonged release intrapocket devices which are inserted at diseased sites. Intrapocket drug delivery system was designed which contain Doxycycline Hyclate an antibacterial agent. The formulations were so developed with an aim to reduce the dose of...
متن کاملDoxycycline hyclate treatment of experimental canine ehrlichiosis followed by challenge inoculation with two Ehrlichia canis strains.
Dogs were experimentally inoculated with Ehrlichia canis Florida to assess the efficacy of doxycycline hyclate for the treatment of acute ehrlichiosis. Treatment with doxycycline eliminated infection in eight of eight dogs. Untreated infected control dogs appeared to eliminate the infection or, alternatively, suppress the degree of ehrlichiemia to a level not detectable by tissue culture isolat...
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ژورنال
عنوان ژورنال: International Journal of Drug Delivery Technology
سال: 2016
ISSN: 0975-4415
DOI: 10.25258/ijddt.v6i4.8899