Quality-adjusted life year difference in patients with predominant negative symptoms of schizophrenia treated with cariprazine and risperidone
نویسندگان
چکیده
منابع مشابه
Cariprazine versus risperidone monotherapy for treatment of predominant negative symptoms in patients with schizophrenia: a randomised, double-blind, controlled trial.
BACKGROUND Although predominant negative symptoms of schizophrenia can be severe enough to cause persistent impairment, effective treatment options are lacking. We aimed to assess the new generation antipsychotic cariprazine in adult patients with predominant negative symptoms. METHODS In this randomised, double-blind, phase 3b trial, we enrolled adults aged 18-65 years with long-term (>2 yea...
متن کاملCariprazine vs Risperidone for Negative Symptoms
Methods: Study subjects had a diagnosis of schizophrenia (DSM-IV-TR) with a duration of ≥2 years and had been clinically stable for ≥6 months but continued to have a Positive and Negative Syndrome Scale (PANSS) negative symptom score of ≥24 plus a score of ≥4 on at least 2 of the 4 core negative PANSS symptoms: blunted affect, passive social withdrawal, lack of spontaneity, and flow of conversa...
متن کاملEfficacy of Risperidone Augmentation with Ondansetron in the Treatment of Negative and Depressive Symptoms in Schizophrenia: A Randomized Clinical Trial
Background: Given the potential role of the 5-hydroxytryptamine-3 receptor in the pathogenesis of schizophrenia, this study was performed to determine whether ondansetron plus risperidone could reduce the negative and depressive symptoms in patients with treatment-resistant schizophrenia.Methods: In a double-blinded, placebo-controlled, randomized trial (IRCT registration # 201112125280N7), in ...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
The Therapeutic Effectiveness of Risperidone on Negative Symptoms of Schizophrenia in Comparison with Haloperidol: A Randomized Clinical Trial
Introduction: A number of research studies have shown that the new generation of neuroleptic medications can more effectively contribute to treating negative symptoms of schizophrenia compared with the first generation by influence cognitive functioning. The present study examined the therapeutic effectiveness of manufactured Risperidone and Haloperidol in Iran on treating the negative symptoms...
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ژورنال
عنوان ژورنال: Journal of Comparative Effectiveness Research
سال: 2017
ISSN: 2042-6305,2042-6313
DOI: 10.2217/cer-2017-0024