QTc dispersion and vulnerability to ventricular fibrillation

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Vulnerability to Fibrillation and the Ventricular-Excitability Curve1

P REVIOUS reports have given a description of the cyclic changes in excitability of both auricle and ventricle of the dog’s heart (I, 2). It was found that the dog’s auricle is ‘vulnerable’ to fibrillation throughout the major dip area of the excitability-recovery curve (3). A study of ventricular vulnerability has now been made. Cats and turtles were used almost exclusively in this investigati...

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Vulnerability to fibrillation and the ventricular-excitability curve.

P REVIOUS reports have given a description of the cyclic changes in excitability of both auricle and ventricle of the dog’s heart (I, 2). It was found that the dog’s auricle is ‘vulnerable’ to fibrillation throughout the major dip area of the excitability-recovery curve (3). A study of ventricular vulnerability has now been made. Cats and turtles were used almost exclusively in this investigati...

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QTc dispersion, hyperglycemia, and hyperinsulinemia.

and Hyperinsulinemia To the Editor: QTc dispersion is an important predictor of cardiac mortality. In the Rotterdam Study,1 persons in the highest tertile (.60 ms) relative to the lowest tertile (,39 ms) of QTc dispersion had a 2-fold risk of cardiac death. The Rotterdam Study also confirms that QTc dispersion is larger in diabetic than in nondiabetic persons. QTc duration and QTc dispersion ar...

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DRUGS AND QTc INTERVAL DISPERSION

The measure of delayed ventricular repolarization most frequently used clinically is the ability of the new chemical entity to prolong the QTc interval on surface electrocardiogram. Intramyocardial dispersion of repolarization appears to play a more important role both in electrical stability of the ventricles and in arrhythmogenesis. The potential importance of myocardial dispersion of refract...

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Carbon monoxide poisoning increases Tpeak–Tend dispersion and QTc dispersion

OBJECTIVES Carbon monoxide (CO) poisoning leads to cardiac dysrhythmia. Increased heterogeneity in ventricular repolarisation on electrocardiogram (ECG) shows an increased risk of arrhythmia. A number of parameters are used to evaluate ventricular repolarisation heterogeneity on ECG. The aim of our study is to investigate the effect of acute CO poisoning on indirect parameters of ventricular re...

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ژورنال

عنوان ژورنال: BMJ

سال: 1996

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.313.7064.1082