Pyrogallol, a generator of free radicals, is emetogenic in Suncus murinus.
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چکیده
منابع مشابه
Vasopressin induces emesis in Suncus murinus.
This paper reports that vasopressin is emetogenic in the house musk shrew Suncus murinus. Either intravenous or intracerebroventricular administration of vasopressin caused vomiting within a few minutes. The ED50 of intravenous vasopressin was as high as 4.67 microg/kg, whereas intracerebroventricularly injected vasopressin was effective at a low dose of 20 ng/brain. The emetogenic target of va...
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Emetic responses to cisplatin and participation of vagal innervation in emesis were studied in suncus. Intraperitoneal and intravenous administration of cisplatin caused dose-dependent emesis. ED50 values, latencies and frequencies were not significantly different between the two administrations. Cis-diaqodiammineplatinum (DAP), an active metabolite of cisplatin, also induced emesis, but with s...
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The musk shrew, Suncus murinus, is an induced ovulator, the cumulus oophorus of which is unusual in several respects: it has no matrix, it always induces the acrosome reaction and it appears to be essential for fertilization. The present study documents distinctive features of the cumulus oophorus before and after ovulation, and of copulation-induced maturation of the ovulatory follicle, which ...
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199 human serum samples were examined for the presence of myxovirus parainfluenza 3 (mpi 3) haemagglutination inhibition (hi) antibodies. or tbe total male sera, 75% and female 70.52% had hi antibody titers of t:32 or greater. the percentage of positive samples increased according to the age grouping of the human beings. these results indicate that mpi 3 virus infection is widespread among the ...
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Reactive metabolites are believed to be responsible for many types of toxicity, including idiosyncratic drug reactions. Bone marrow is a frequent target of idiosyncratic reactions, and, since these reactions have characteristics that suggest involvement of the immune system, the formation of reactive metabolites by leucocytes could also play a role in the aetiology of idiosyncratic drug reactio...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1993
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)51343-9