Pyridoxine-dependent Seizures: Long-term Follow-up of Two Cases with Clinical and MRI Findings, and Pyridoxine Treatment
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چکیده
منابع مشابه
Pyridoxine-dependent seizures: 10-year follow-up of eight cases.
Eight children with pyridoxine-dependent seizures (PDS) were seen over a period of 10 years. Of those children, 6 are on regular follow-up. Four of the children were seen in one family. All the patients presented with refractory seizures, mainly neonatal status epilepticus. Though PDS is a rare condition, it must be considered in all cases with refractory seizures, particularly in children youn...
متن کامل[Pyridoxine dependent seizures].
Pyridoxine dependent seizures is a rare autosomal recessive disorder. Its manifestations are intractable epilepsy leading to death in status epilepticus. Treatment with pyridoxine prevents the seizures and normalizes the EEG. Early diagnosis is important for the intellectual outcome. In Denmark, the disease has occurred in a child of healthy Tamil immigrants, who are first cousins. The child's ...
متن کاملPyridoxine dependent seizures--a wider clinical spectrum.
We report 4 infants with pyridoxine dependent seizures who had clinical features that led to diagnostic uncertainty. Their clinical course was unusual in 1 or more of the following: later onset of initial seizures; a seizure free period after taking of anticonvulsants, but before taking of pyridoxine; a long remission after withdrawal of pyridoxine; and atypical seizure type. This report illust...
متن کاملNeglected Atypical Pyridoxine Dependent Seizures
Omid Yaghini, MD; Mohammad-Amir Shahkarami*, MD; Somayeh Shamsaii, MD Pediatrics Department, Isfahan University of Medical Sciences, Isfahan, IR Iran Received: Nov 02, 2009; Accepted: Mar 13, 2010 Vitamin B6 (pyridoxine) dependent seizure (PDS) is an autosomal-recessively inherited disorder which starts within a few hours of birth or even earlier, and can cause intrauterine seizures[1,2]. It oc...
متن کاملLong-term outcome in pyridoxine-dependent epilepsy.
AIM The long-term outcome of the Dutch pyridoxine-dependent epilepsy cohort and correlations between patient characteristics and follow-up data were retrospectively studied. METHOD Fourteen patients recruited from a national reference laboratory were included (four males, 10 females, from 11 families; median age at assessment 6y; range 2y 6mo-16y). The following data were retrieved: sex; age ...
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ژورنال
عنوان ژورنال: Journal of Tropical Pediatrics
سال: 2002
ISSN: 0142-6338,1465-3664
DOI: 10.1093/tropej/48.5.303