منابع مشابه
Pyoderma gangrenosum.
Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...
متن کاملThe role of interleukin-1β in pyoderma gangrenosum
IL: interleukin PAPA: pyogenic arthritis, pyoderma gangrenosum, and acne PASH: pyoderma gangrenosum, acne, and suppurative hidradenitis PG: pyoderma gangrenosum TNF: tumor necrosis factor UC: ulcerative colitis INTRODUCTION Pyoderma gangrenosum (PG) is a rare, inflammatory, and necrotizing disease that belongs to the group of neutrophilic dermatosis. The pathogenesis of PG remains unknown. In t...
متن کاملIbrutinib-induced pyoderma gangrenosum.
710 started an oral ibrutinib therapy (3 × 140 mg/d), due to B-CLL. An ulcer biopsy revealed lymphocyte and neutrophil infiltration. No histopathologic signs of carcinoma or vasculitis were observed. After consultation with a hematologist, a tentative diagnosis of ibrutinib-induced pyoderma gangrenosum (PG) was established. In addition to ibrutinib discontinuation, daily prednisone dose was inc...
متن کاملPyoderma gangrenosum – a review
Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes may also be involved. Course can be mild or malignant, chronic or relapsing with...
متن کاملNicotine for pyoderma gangrenosum.
A 35-year-old man with no past medical illness developed bloody diarrhea with up to 12 loose stools per day and abdominal pain in February 1984. He had smoked 1 pack of cigarettes per day for 16 years until he stopped smoking 2 months prior to the onset of his illness. In March 1984, he was hospitalized because of toxic dilatation of the colon (toxic megacolon). Treatment consisted of intraveno...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2007
ISSN: 0007-0963,1365-2133
DOI: 10.1111/j.1365-2133.2007.08202.x