PW03-022 – Neutrophilic skin disease and inflammation
نویسندگان
چکیده
منابع مشابه
PW03-022 – Neutrophilic skin disease and inflammation
Introduction Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia. This cluster of syndromes became known as Sweet’s syndrome. There have been many published cases in children of neutrophilic dermatoses and fever which are labeled as Sweet’s syndrome. Recently, however, neutrophilic dermatoses h...
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Introduction Predominantly neutrophilic inflammatory infiltrates are seen in a subset of chronic urticaria patients, with lesions that tend to be less itchy and poorly responsive to antihistamine therapy.[1,2] There have been reports of patients with neutrophilic dermatoses presenting with extracutaneous inflammation.[3] We present two patients with neutrophilic urticaria and extracutaneous sym...
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It is unknown whether neutrophilic inflammations can be regulated by T cells. This question was analyzed by studying acute generalized exanthematous pustulosis (AGEP), which is a severe drug hypersensitivity resulting in intraepidermal or subcorneal sterile pustules. Recently, we found that drug-specific blood and skin T cells from AGEP patients secrete high levels of the potent neutrophil-attr...
متن کاملNeutrophilic inflammation in childhood asthma
A lthough asthma has its highest prevalence in childhood, it is generally less severe than in adolescents and adults. Whether the high population prevalence is because symptoms are more noticed by parents or whether the more physically active lifestyle and natural inquisitiveness of children, particularly young children, unmasks bronchial hyperresponsiveness and related symptoms remains elusive...
متن کاملPW03-025 - Procaspase-1 contributes to inflammation via NF-KB
Introduction Caspase-1 is a pro-inflammatory enzyme which gets activated by autoprocessing following the assembly of multiprotein complexes called inflammasomes. Mature caspase-1 is responsible for the activation of the proinflammatory cytokines interleukin (IL)-1b and IL-18. Luksch and colleagues reported naturally occurring CASP1 genetic variants in patients suffering from unexplained recurre...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a248