Putting up Beans

Putting up and Putting Down: Tolerance Reconsidered

Putting up with self.

Five years ago Denise Faustman stunned the biomedical world--and not in a good way, it seemed. She declared that she had cured diabetic mice by getting them to regrow their insulin-producing beta cells, a finding that, if it could be translated to humans, would spare the million-odd Americans with type 1 diabetes their daily needle pricking and insulin dosing. Since her announcement, the academ...

Basement membrane: Putting up the barriers

The basement membrane is a highly organized extracellular matrix with adhesive and barrier functions. Assembly of this matrix uses two types of cell surface receptor, integrins and dystroglycan, to coordinate formation of a polygonal network of laminin, a major basement membrane protein.

HIV Is Putting Up Less Resistance

The development of combination antiretroviral therapy (ART) has been a major achievement of modern medicine, turning a fatal condition into a relatively manageable condition for millions of persons globally. During the past decade, antiretroviral drugs with increased potency, reduced toxicity, and availability as several fixed-dose combinations (1 pill daily) have expanded acceptance by patient...

up the beans talk: an evolutionary organizational structure for libraries

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