Putting numbers on mycobacterium activated T cell subsets

Putting Numbers on Intangible Benefits

Intangible benefits have been a thorn in the side of information technology project valuation efforts. These benefits are often comparable to tangible benefits in magnitude, and so should not be ignored. Yet, unless we can attach numbers to them, it is difficult to combine them in a consistent way with tangible benefits to reduce the chances of underestimating the true value of a project. The l...

The Immunomodulatory Effect of Cyclophosphamide on Regulation of T-Cell Subsets and Antigen Presenting Cells.

Cross-regulation of CD86 by CD80 differentially regulates T helper responses from Mycobacterium tuberculosis secretory antigen-activated dendritic cell subsets.

We report that stimulation of Mycobacterium tuberculosis secretory antigen- and tumor necrosis factor alpha-matured BALB/c mouse bone marrow dendritic cells (BMDCs) with anti-CD80 monoclonal antibody up-regulated CD86 levels on the cell surface. Coculture of these BMDCs with naïve, allogeneic T cells now down-regulated T helper cell type 1 (Th1) responses and up-regulated suppressor responses. ...

CD4(+) T-cell subsets that mediate immunological memory to Mycobacterium tuberculosis infection in mice.

We have studied CD4(+) T cells that mediate immunological memory to an intravenous infection with Mycobacterium tuberculosis. The studies were conducted with a mouse model of memory immunity in which mice are rendered immune by a primary infection followed by antibiotic treatment and rest. Shortly after reinfection, tuberculosis-specific memory cells were recruited from the recirculating pool, ...

imbalance of t-cell subsets in iranian allergic rhinitis patients

r'iwenty-nine patients were studied to determine the number of cj).j+ tscell subsets in iranian allergic rhinitis patients. the result was compared with that a/twenty-four nonatopic controls. the number of11 and cds+t cell')and levels ofspeafic ige and /g(;4 against weed pollens were also studied the number of lymphocyte subset, tltat is, cd-/+ c/)29+and c1jf cj)451t cells were determined hy do...