Putative CSF protein biomarker candidates for amnestic mild cognitive impairment
نویسندگان
چکیده
منابع مشابه
Prospective memory in amnestic mild cognitive impairment.
Individuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-bas...
متن کاملThalamic Shape and Cognitive Performance in Amnestic Mild Cognitive Impairment
OBJECTIVE This study aimed to investigate thalamic shape alterations and their relationships with various episodic memory impairments in subjects with amnestic mild cognitive impairment (aMCI). METHODS We compared volumes and morphological alterations of the thalamus between aMCI subjects and healthy controls. In addition, we investigated the correlation between thalamic deformations and vari...
متن کاملInformant-reported cognitive symptoms that predict amnestic mild cognitive impairment
BACKGROUND Differentiating amnestic mild cognitive impairment (aMCI) from normal cognition is difficult in clinical settings. Self-reported and informant-reported memory complaints occur often in both clinical groups, which then necessitates the use of a comprehensive neuropsychological examination to make a differential diagnosis. However, the ability to identify cognitive symptoms that are pr...
متن کاملMismatch negativity (MMN) amplitude as a biomarker of sensory memory deficit in amnestic mild cognitive impairment
It has been suggested that changes in some event-related potential (ERP) parameters associated with controlled processing of stimuli could be used as biomarkers of amnestic mild cognitive impairment (aMCI). However, data regarding the suitability of ERP components associated with automatic and involuntary processing of stimuli for this purpose are not conclusive. In the present study, we studie...
متن کاملPosterior Cingulate Lactate as a Metabolic Biomarker in Amnestic Mild Cognitive Impairment
Mitochondrial dysfunction represents a central factor within the pathogenesis of the Alzheimer's disease (AD) spectrum. We hypothesized that in vivo measurements of lactate (lac), a by-product of glycolysis, would correlate with functional impairment and measures of brain health in a cohort of 15 amnestic mild cognitive impairment (aMCI) individuals. Lac was quantified from the precuneus/poster...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Translational Neuroscience
سال: 2010
ISSN: 2081-6936,2081-3856
DOI: 10.2478/v10134-010-0004-0