Purinyl N1-Directed Aromatic C–H Oxidation in 6-Arylpurines and 6-Arylpurine Nucleosides

06Seed Dispersal Ch 6

Despite the accumulation of a considerable body of literature about frugivory and seed dispersal of fleshy-fruited plants by vertebrates during the last decades (e.g. reviews in Howe and Smallwood, 1982; van der Pijl, 1982; Janzen, 1983; Howe, 1986; Howe and Westley, 1988; Stiles, 1989; Jordano, 2000; Herrera, 2002), and also previous editions of the Frugivores and Seed Dispersal: International...

Cytostatic and Antiviral 6-Arylpurine Ribonucleosides IX. Synthesis and Evaluation of 6-Substituted 3-Deazapurine Ribonucleosides

A series of 3-deazapurine ribonucleosides 5a–5l bearing diverse C-substituents (alkyl, aryl and heteroaryl) in the position 6 were prepared by Pd-catalyzed cross-coupling reactions of either free 6-chloro-3-deazapurine ribonucleoside 4 or its acetyl protected congener 3 followed by deprotection. An improved synthesis of the starting 4-chloro-1-(2,3,5-tri-O-acetylβ-D-ribofuranosyl)-1H-imidazo[4,...

فرآیند تولید ترکیب انفجاری CH-6(علمی-ترویجی)

Preparation of 2- and 6-pyridones of N1-methylnicotinamide.

In the course of experiments designed to elucidate the structure of reduced diphosphopyridine nucleotide (DPNH) (12), it became necessary to prepare the 2and 6-pyridones of iV-methylnicotinamidel by oxidation of the latter. Huff (5) has described the preparation of N’-methyl-6-pyridone-3-carboxylic acid by alkaline ferricyanide oxidation of either trigonelline or N’-methylnicotinamide. The acid...

Use of nucleosides in resistance to 6-thioguanine.

Ascites cell tumors were found to cleave thioguanine riboside relatively rapidly. In tumor cell lines lacking the ribonucleotide pyrophosphorylase necessary for formation of thioguanine ribonucleotide, thioguanine riboside was converted to nucleotide to a small extent. This nucleotide formation was enhanced, after a short time lag, by 9-methyl thioguanine. The nucleoside, adenine arabinoside, w...