Purification of Beef Adrenocorticotropic Hormone (ACTH)
نویسندگان
چکیده
منابع مشابه
The effects of adrenocorticotropic hormone (ACTH) in lepromatous lepra reaction.
Lepra reaction in lepromatous leprosy is a most troublesome acute incident in the chronic, drawn-out course of the disease. So far, there has been no way of controlling satisfactorily the characteristic fever, malaise, joint and muscle aches, and cutaneous lesions' which periodically beset many of these patients. Since adrenocorticotropic hormone (ACTH) has produced marked symptomatic benefit i...
متن کاملTreatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH) gel
PURPOSE A synthetic adrenocorticotropin (ACTH) analog has shown efficacy in Europe as primary and secondary therapy for nephrotic syndrome, but there is no published experience using the natural, highly purified ACTH gel formulation, available in the United States, for nephrotic syndrome. We therefore investigated the use of ACTH gel for nephrotic syndrome in the United States. PATIENTS AND M...
متن کاملIsolated Adrenocorticotropic Hormone (acth) Deficiency Associated with Hashimoto's Disease
Isolated ACTH deficiency (IAD) is a rare disease which is characterized by secondary adrenal insufficiency with low cortisol production and normal secretion of pituitary hormones other than ACTH. Isolated ACTH deficiency has rare association with Hashimoto’s disease which is characterized by autoimmune origin. This suggests the possibility of common autoimmune process affecting both the pituita...
متن کاملEffects of exogenous adrenocorticotropic hormone (ACTH) upon pituitary ACTH concentration after prolonged cortisone treatment and stress.
Symptoms and metabolic abnormalities closely resembling those of hypoadrenalism have been reported following cessation of prolonged treatment with adrenal steroids (1-5). Sudden death following surgery has been reported in association with this syndrome and has been ascribed to failure of the hypothalamic-pituitary-adrenal system to respond to stress (6-9). Since prolonged administration of cor...
متن کاملIodinated Derivatives of Adrenocorticotropic Hormone PREPARATION OF IODINATED ~x’-~~-ACTH WITH FULL HORMONAL ACTIVITY*
Iodinated derivatives of adrenocorticotropic hormone (ACTH) were prepared with the use of NaI and chloramine-T and isolated by isoelectric focusing. The monoiodinated derivative (p1 7.6) was resolved into [monoiodoTyr2]ACTH and [monoiodoTyrZ3]ACTH by chromatography on columns of carboxymethylcellulose. Both monoiodo-AC’IH species exhibited only 30% of the maximum hormonal activity when assayed ...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy
سال: 1952
ISSN: 0021-4280
DOI: 10.2183/pjab1945.28.351