منابع مشابه
Science with a punch
There are changes afoot in the way that US granting agencies, most notably the NIH, evaluate proposals. Change can be a good thing, and it is probably high time that the NIH reassessed how grants are evaluated. Frankly, I was becoming blasé about the entire granting process. It seemed that once I became inured to the low probability of funding, competition from the mega-labs, and the shift towa...
متن کاملDigital Punch Cutting
Digital punch cutting is today’s font technology. There are three different methods available for getting alphabets into digital form : hand-digitizing, auto-tracing and direct design on a workstation screen. The advent of intelligent font scaling requires us to ensure the ‘optical’ quality of a font and also the ‘numerical’ quality of its data; this, in turn, means that new procedures have to ...
متن کاملTriple punch against trypanosomes
Fat cooperation keeps sleeping sickness at bay, say Molina-Portela et al. (page 1721). The authors find that all three components of a human high density cholesterol complex are needed to kill disease-causing trypanosomes. Trypanosomes cannot synthesize their own fats, so they feed on the host's portion, which in humans and some other primates includes a cholesterol complex known as the trypano...
متن کاملThe one-two punch
The vitamin A metabolite retinoic acid (RA) regulates gene transcription by activating the nuclear receptors RAR and PPARβ/δ and their cognate lipid binding proteins CRABP-II, which delivers RA to RAR, and FABP5, which shuttles the hormone to PPARβ/δ. In preadipocytes, RA signals predominantly through CRABP-II and the RAR isotype RARγ to induce the expression of hallmark markers of preadipocyte...
متن کاملThe serratus punch.
Shoulder pain is common, especially with overhead tasks. A common misconception is that the rotator cuff should be trained with internal and external rotation exercises. The shoulder girdle is complex due to it’s inherent instability. This allows a tremendous range of mobility, but comes with a price. Namely, overuse injuries from repetitive strain especially with lifting, throwing, striking, e...
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ژورنال
عنوان ژورنال: BMJ
سال: 1949
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4600.386