Pulse Intravenous Cyclophosphamide Therapy in Pemphigus
نویسندگان
چکیده
منابع مشابه
Pulse intravenous cyclophosphamide therapy in pemphigus.
BACKGROUND Adjuvant therapy is commonly used in pemphigus to mitigate the high morbidity and mortality associated with the use of corticosteroids and improve disease control. However, these adjuvant agents are not without adverse effects of their own, including an increased risk of malignancy with the use of oral immunosuppressives. Intravenous pulse cyclophosphamide, which may be more efficaci...
متن کاملDexamethasone-cyclophosphamide pulse therapy in pemphigus.
Fifty patients with pemphigus (45 pemphigus vulgaris, 5 pemphigus foliaceus) were treated with dexamethasone-cyclophosphamide pulse therapy. The pulse consisted of 136 mg dexamethasone dissolved in 5% dextrose given in a drip over a period of 1-2 hours on 3 consecutive days. In addition, 500 mg cyclophosphamide was added in the drip on the first day. Such pulses were given at monthly intervals....
متن کاملCyclophosphamide pulse therapy in idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis (IPF) is a progressive disorder with poor prognosis. Response to treatment is infrequent and the use of immunosuppressive agents other than corticosteroids is the subject of ongoing discussion because of uncertain efficacy and side-effects. To determine the efficacy and safety of cyclophosphamide pulse therapy in IPF, this study retrospectively analysed 18 patients...
متن کاملIntravenous cyclophosphamide pulse therapy in juvenile dermatomyositis. A review of efficacy and safety.
OBJECTIVES To assess the efficacy and safety of intravenous cyclophosphamide (CYP) used in severe and refractory juvenile dermatomyositis (JDM). METHODS Retrospective case note review of the outcome of 12 patients. RESULTS Assessment at 6 months of therapy in 10 of the 12 patients showed a significant improvement in muscle function as assessed by the Childhood Myositis Assessment Scale (CMA...
متن کاملIntravenous cyclophosphamide pulse therapy in Japanese children with systemic lupus erythematosus.
BACKGROUND Intravenous cyclophosphamide (IVCY) pulse therapy has been used for lupus nephritis since the latter half of the 1980s; it has been shown to be effective for lupus nephritis and vasculitis and has become a standard therapy for the diffuse proliferative type of lupus nephritis in adults. IVCY therapy has also come to be used in children. This paper reports the long-term outcomes of IV...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 1999
ISSN: 0003-987X
DOI: 10.1001/archderm.135.1.57