Pulmonary hypertension and chronic cutaneous lupus erythematosus: association with the lupus anticoagulant

Chronic cutaneous (discoid) lupus erythematosus.

Cutaneous Lupus Erythematosus: Epidemiology, Association with Systemic Lupus Erythematosus and Comorbidity

Lupus erythematosus (LE) is a chronic disease that includes a broad spectrum of symptoms. Lupus is Latin for wolf; perhaps the skin lesions were thought to resemble wolf bites. LE is included among the connective tissue diseases and is divided into systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE). These can occur together or separately. The classification of CLE was di...

The lupus anticoagulant, pulmonary thromboembolism, and fatal pulmonary hypertension.

A patient with a circulating lupus anticoagulant in the absence of systemic lupus erythematosus developed recurrent deep venous thromboses and pulmonary emboli. Pulmonary emboli recurred despite prolonged oral anticoagulant therapy and resulted in fatal pulmonary arterial hypertension. Extended anticoagulant therapy alone may not prevent recurrent thromboembolism in patients with a lupus antico...

Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant.

The lupus anticoagulant was found in the plasma of 31 of 60 patients with systemic lupus erythematosus and other connective tissue disorders (mixed connective tissue disease, systemic vasculitis, polyarteritis nodosa, primary sicca syndrome, discoid lupus, Behcet's syndrome, and systemic sclerosis). Strong associations were found with biological false positive seroreaction for syphilis and thro...

Chronic cutaneous lupus erythematosus with systemic symptoms or systemic lupus erythematosus?

A 50 year old female presented to our hospital with complaints of hypopigmented itchy plaques over back and both pinnae since 6 years. She also complained of similar lesions in the scalp which were associated with loss of hair. History dates back to 6 years when patient noted an itchy papule on the upper back which gradually increased in size along with development of similar lesions over both ...