Pulmonary granulomas after tumour necrosis factor alpha antagonist therapy
نویسندگان
چکیده
منابع مشابه
Pulmonary granulomas after tumour necrosis factor alpha antagonist therapy.
Tumour necrosis factor alpha (TNFalpha) antagonists are an established therapeutic option in Crohn's disease and rheumatoid arthritis. In recently published studies these agents have been used with great success, but little is known about any side effects or long term consequences. They increase the frequency of infections with mycobacteria, where TNFalpha is thought to be an important host def...
متن کاملScreening for latent tuberculosis before tumour necrosis factor antagonist therapy.
References 1 Morice AH, Millqvist E, Belvisi MG, et al. Expert opinion on the cough hypersensitivity syndrome in respiratory medicine. Eur Respir J 2014; 44: 1132–1148. 2 Pullerits T, Ternesten-Hasséus E, Johansson EL, et al. Capsaicin cough threshold test in diagnostics. Respir Med 2014; 108: 1371–1376. 3 Faruqi S, Thompson R, Wright C, et al. Quantifying chronic cough: objective versus subjec...
متن کاملDetection of tumour necrosis factor alpha in sarcoidosis and tuberculosis granulomas using in situ hybridisation.
AIMS To determine the site of tumour necrosis factor alpha (TNF alpha) product and mRNA in granulomas. METHOD In situ hybridisation with digoxigenin labelled or biotinylated oligonucleotide probes was used to demonstrate the presence of total mRNA, and then the presence of TNF alpha mRNA in the biopsy specimens of 37 granulomas (31 sarcoidosis, six tuberculosis). RESULTS TNF alpha mRNA was ...
متن کاملTreatment of ocular cicatricial pemphigoid with the tumour necrosis factor alpha antagonist etanercept.
Sir, Cicatricial pemphigoid (CP) is a rare autoimmune subepithelial blistering disease that predominantly affects the mucous membranes with scarring (1). The disease is characterized by the involvement of muco-cutaneous sites, among them ocular invo-lvement, which can lead to blindness. Mild forms of the disease may be controlled by anti-inflammatory drugs, such as dapsone, whereas severe forms...
متن کاملCanadian Association of Gastroenterology Clinical Practice Guidelines: The use of tumour necrosis factor-alpha antagonist therapy in Crohn's disease.
BACKGROUND Guidelines regarding the use of infliximab in Crohn's disease were previously published by the Canadian Association of Gastroenterology in 2004. However, recent clinical findings and drug developments warrant a review and update of these guidelines. OBJECTIVE To review and update Canadian guidelines regarding the use of tumour necrosis factor-alpha antibody therapy in both luminal ...
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ژورنال
عنوان ژورنال: Thorax
سال: 2003
ISSN: 0040-6376
DOI: 10.1136/thorax.58.3.278