Publisher Correction: Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution
نویسندگان
چکیده
A Correction to this paper has been published: https://doi.org/10.1038/s41588-021-00849-4.
منابع مشابه
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.
To study the evolutionary dynamics of regulatory DNA, we mapped >1.3 million deoxyribonuclease I-hypersensitive sites (DHSs) in 45 mouse cell and tissue types, and systematically compared these with human DHS maps from orthologous compartments. We found that the mouse and human genomes have undergone extensive cis-regulatory rewiring that combines branch-specific evolutionary innovation and los...
متن کاملEnhancer Divergence and cis-Regulatory Evolution in the Human and Chimp Neural Crest
cis-regulatory changes play a central role in morphological divergence, yet the regulatory principles underlying emergence of human traits remain poorly understood. Here, we use epigenomic profiling from human and chimpanzee cranial neural crest cells to systematically and quantitatively annotate divergence of craniofacial cis-regulatory landscapes. Epigenomic divergence is often attributable t...
متن کاملRecent mating-system evolution in Eichhornia is accompanied by cis-regulatory divergence.
The evolution of predominant self-fertilization from cross-fertilization in plants is accompanied by diverse changes to morphology, ecology and genetics, some of which likely result from regulatory changes in gene expression. We examined changes in gene expression during early stages in the transition to selfing in populations of animal-pollinated Eichhornia paniculata with contrasting mating p...
متن کاملPredominant contribution of cis-regulatory divergence in the evolution of mouse alternative splicing
Divergence of alternative splicing represents one of the major driving forces to shape phenotypic diversity during evolution. However, the extent to which these divergences could be explained by the evolving cis-regulatory versus trans-acting factors remains unresolved. To globally investigate the relative contributions of the two factors for the first time in mammals, we measured splicing diff...
متن کاملSystematic Detection of Polygenic cis-Regulatory Evolution
The idea that most morphological adaptations can be attributed to changes in the cis-regulation of gene expression levels has been gaining increasing acceptance, despite the fact that only a handful of such cases have so far been demonstrated. Moreover, because each of these cases involves only one gene, we lack any understanding of how natural selection may act on cis-regulation across entire ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Genetics
سال: 2021
ISSN: ['1546-1718', '1061-4036']
DOI: https://doi.org/10.1038/s41588-021-00849-4