<p>The LINC01260 Functions as a Tumor Suppressor via the miR-562/CYLD/NF-κB Pathway in Non-Small Cell Lung Cancer</p>
نویسندگان
چکیده
منابع مشابه
MiR-142-3p functions as a potential tumor suppressor directly targeting HMGB1 in non-small-cell lung carcinoma.
BACKGROUND microRNAs (miRNAs) play a significant role in cancer development and progression by regulating the expression of oncogenes or tumor suppressor genes. Previous study using microarrays demonstrated that miR-142-3p was downregulated in patients with Non-small-cell lung carcinoma (NSCLC). However, the functional role of miR-142-3p in NSCLC is still unclear. MATERIAL AND METHOD Real-tim...
متن کاملmiR-215 functions as a tumor suppressor and directly targets ZEB2 in human non-small cell lung cancer
MicroRNA-215 (miR-215) has previously been demonstrated to be dysregulated in a number of human malignancies and to be correlated with tumor progression. However, the expression and function of miR-215 in non-small cell lung cancer (NSCLC) has remained to be elucidated. Therefore, the present study aimed to investigate the effects of miR-215 in NSCLC tumorigenesis and development. Reverse trans...
متن کاملmiR-32 functions as a tumor suppressor and directly targets SOX9 in human non-small cell lung cancer
PURPOSE MicroRNA-32 (miR-32) is dysregulated in certain human malignancies and correlates with tumor progression. However, its expression and function in non-small cell lung cancer (NSCLC) remain unclear. Thus, the aim of this study was to explore the effects of miR-32 expression on NSCLC tumorigenesis and development. METHODS Using real-time quantitative reverse-transcription polymerase chai...
متن کاملmiR-32 functions as a tumor suppressor and directly targets SOX9 in human non–small cell lung cancer [Retraction]
[This retracts the article on p. 1773 in vol. 8, PMID: 26229485.].
متن کاملP42 Ebp1 functions as a tumor suppressor in non-small cell lung cancer
Although the short isoform of ErbB3-binding protein 1 (Ebp1), p42 has been considered to be a potent tumor suppressor in a number of human cancers, whether p42 suppresses tumorigenesis of lung cancer cells has never been clarified. In the current study we investigated the tumor suppressor role of p42 in non-small cell lung cancer cells. Our data suggest that the expression level of p42 is inver...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2020
ISSN: 1178-6930
DOI: 10.2147/ott.s253730