PTH-096 Oral Ciclopsorin in Steroid Refractory, Acute, Severe Ulcerative Colitis
نویسندگان
چکیده
منابع مشابه
Cyclosporine in the treatment of severe steroid refractory ulcerative colitis: a retrospective analysis of 24 cases.
BACKGROUND Cyclosporine A (CsA) has been found to be the first successful therapy used in the recovery of patients with steroid-refractory ulcerative colitis (UC). However, the long-term benefits of cyclosporine remain questionable. We report our results on the use of CsA in patients with severe steroid-refractory UC. METHODS The records of all patients with steroid refractory UC treated with...
متن کاملDoes the Cyclosporine Still Have a Potential Role in the Treatment of Acute Severe Steroid-Refractory Ulcerative Colitis?
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon characterized by diffuse mucosal inflammation. Acute severe colitis, a potentially lethal condition requiring hospitalization and intensive medical treatment can develop in 18% to 25% of patients with UC. Although intravenous corticosteroids are the mainstay of conventional medical treatment in this condition, about 30% to 4...
متن کاملSevere refractory ulcerative colitis in a young lady.
A 39-year-old lady presented with bloody diarrhea for 6 weeks, and pedal edema, abdominal distension and reduced urine output for 3 days. Six weeks back she de veloped predominantly watery stools with blood and mu cus, large volume, 10-12 times/day. She also had mild pre dominantly non-colicky abdominal pain. Three days prior to hospitalization she developed increased pain, abdomi nal diste...
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The idiopathic inflammatory bowel diseases comprise mainly two types of intestinal disorder, Crohn disease and ulcerative colitis. The clinical course is marked by exacerbations and remissions that occur spontaneously in response to treatment or intercurrent illness. The disease affects approximately 240,000 patients in the UK. Acute severe ulcerative colitis is a medical emergency; prompt effe...
متن کاملCyclosporin for refractory ulcerative colitis.
Approximately 15% of patients with ulcerative colitis will have a severe attack requiring hospitalisation for intravenous steroids at some stage in their illness. Sixty per cent of patients treated with corticosteroids will be symptom free by the end of five days, 15% will have significant improvement, and 25% will not improve. Those who fail to improve may be treated with intravenous cyclospor...
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ژورنال
عنوان ژورنال: Gut
سال: 2013
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2013-304907.583