PTCT-03RELAPSE MEDULLOBLASTOMA IN INFANT: COMPLETE RESPONSE WITH TEMOZOLOMIDE AND IRINOTECAN

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Dramatic response to temozolomide, irinotecan, and bevacizumab for recurrent medulloblastoma with widespread osseous metastases.

There is little evidence to guide the choice of chemotherapeutic agents for osseous metastases in medulloblastoma. Recently, triple therapy with temozolomide, irinotecan, and bevacizumab has been reported to have efficacy in recurrent medulloblastoma, and this regimen alone and in combination with other agents has been tested in several early-phase clinical trials. Here we report a 20-year-old ...

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ژورنال

عنوان ژورنال: Neuro-Oncology

سال: 2015

ISSN: 1522-8517,1523-5866

DOI: 10.1093/neuonc/nov229.03