Psychotropic Medications and QTc Parameters in a Nigerian Cohort

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QTc prolongation, torsades de pointes, and psychotropic medications.

BACKGROUND Prolongation of the corrected QT (QTc) interval is a key issue for patients who receive psychotropic medications. Such patients may have baseline clinical risk factors for QTc prolongation, and many psychotropic medications may further prolong this interval. This has great clinical relevance, as QTc prolongation is linked with dangerous arrhythmias, especially torsades de pointes (Td...

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Psychotropic Medications, Associated QTc Prolongation, and Sudden Cardiac Death: A Review for Clinicians

Prolongation of QTC is an electrocardiographic finding indicating prolongation of cardiac repolarization, which increases the risk for torsades de pointes, a form of ventricular tachycardia that can lead to sudden cardiac death. Sudden cardiac death in the setting of antipsychotic treatment was first described in the 1960s with thioridazine; since that time, many other psychotropic medications ...

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Utilisation of psychotropic medications

The timely article by Verdoux & Begaud ́ hopefully begins to redress the imbalance between randomised controlled trials and other ways of evaluating drug treatments. I would like to present further evidence for the ‘gap between guidelines and utilisation . . . for psychotropic medications’ (Verdoux & Begaud, 2004). ́ Using the Drug Report of the German Public Health Insurance (Schwabe & Pfaffrath...

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Utilisation of psychotropic medications

The timely article by Verdoux & Begaud ́ hopefully begins to redress the imbalance between randomised controlled trials and other ways of evaluating drug treatments. I would like to present further evidence for the ‘gap between guidelines and utilisation . . . for psychotropic medications’ (Verdoux & Begaud, 2004). ́ Using the Drug Report of the German Public Health Insurance (Schwabe & Pfaffrath...

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ژورنال

عنوان ژورنال: British Journal of Medicine and Medical Research

سال: 2012

ISSN: 2231-0614

DOI: 10.9734/bjmmr/2012/1264