Psychosocial dwarfism: Normal Somatomedin (SM)
نویسندگان
چکیده
منابع مشابه
Psychosocial Dwarfism : Detection , Evaluation and Managkment
Environmentally-induced growth retardation associated with psychosocial deprivation, emotional stress and/or neglect is probably the most common single cause of deviant growth in infants and children in the United States today. All too often, however, the child's small stature is ascribed to other etiologies because environmental factors are unappreciated. In 1967, Powell and associates describ...
متن کامل[Somatomedin (bioassay) response to long-term growth hormone treatment of idiopathic pituitary dwarfism].
Serum somatomedin (SM) activity by bioassay was measured in 46 idiopathic pituitary dwarfs before and during long-term hGH treatment. The mean (+/- SD) pretreatment SM activity was 0.38 +/- 0.17 U/ml. The mean (+/- SD) pretreatment annual growth rate was 3.4 +/- 1.0 cm/year. None of the patients had a SM activity within the normal range of age-matched controls. The mean SM activity 1 day post G...
متن کاملLow somatomedin-C (Sm-C) concentrations measured by direct radioimmunoassay in patients with chronic renal failure.
Ten patients suffering from chronic renal failure and undergoing regular hemodialysis were tested immediately before and immediately after a 3-hour dialysis. Serum levels of immunoreactive Sm-C, estimated on unextracted non acidified serum at non equilibrium, were significantly lower than in normal controls and no consistent modifications were observed after dialysis.
متن کاملSomatomedin C deficiency in Asian sisters.
Two sisters of Asian origin showed typical clinical and biochemical features of primary somatomedin C (SM-C) deficiency (Laron dwarfism). Abnormalities of SM-C binding proteins were observed, one sister lacking the high molecular weight (150 Kd) protein.
متن کاملSomatomedin-A (Sm-A) bioactivity in serum and amniotic fluid as related to weight in the fetal pig.
Serum and amniotic fluid Sm-A bioactivity has been assayed in the fetal pig using a double labelling technique. 3H-thymidine activity was always higher in fetuses and lower in sows than 35S activity. 35SO4 uptake was not stimulated or was inhibited in about 30 p. 100 of the fetal sera. 3H-thymidine uptake was stimulated in all of them. There was a significant correlation (P less than 0.001) bet...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1975
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197508000-00077