Psychedelic and nonpsychedelic LSD and psilocybin for cluster headache

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Psychedelic and nonpsychedelic LSD and psilocybin for cluster headache.

Simos and colleagues reported that Ontario surgeons and oncologists don’t follow guidelines when ordering imaging in women with early-stage breast cancer.1 The paper joins tens, if not hundreds, of similar articles describing the failure of practising physicians to follow guidelines. Over the last two decades, repeated attempts have been made to “transfer” or “translate” knowledge to practising...

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Response of cluster headache to psilocybin and LSD.

The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on th...

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Values and beliefs of psychedelic drug users: a cross-cultural study.

Psychedelic drugs such as LSD and psilocybin are often claimed to be capable of inducing life-changing experiences described as mystical or transcendental, especially if high doses are taken. The present study examined possible enduring effects of such experiences by comparing users of psychedelic drugs (n = 88), users of nonpsychedelic illegal drugs (e.g., marijuana, amphetamines) (n = 29) and...

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Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin

What is the level of consciousness of the psychedelic state? Empirically, measures of neural signal diversity such as entropy and Lempel-Ziv (LZ) complexity score higher for wakeful rest than for states with lower conscious level like propofol-induced anesthesia. Here we compute these measures for spontaneous magnetoencephalographic (MEG) signals from humans during altered states of consciousne...

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Cluster headache and depression.

OBJECTIVE As cluster headache (CH) is often referred to as "suicide headache," we wanted to assess the prevalence of depression in CH patients, and to investigate determinants of depression such as sleep disturbances. METHODS In a cross-sectional, web-based, validated questionnaire study among 462 well-defined CH patients and 177 controls, we diagnosed CH according to the ICHD-III. We assesse...

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ژورنال

عنوان ژورنال: Canadian Medical Association Journal

سال: 2016

ISSN: 0820-3946,1488-2329

DOI: 10.1503/cmaj.1150082