Pseudomonas aeruginosa defense systems against microbicidal oxidants
نویسندگان
چکیده
منابع مشابه
Bactericidal Effect against Pseudomonas Aeruginosa
Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Pathology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Central Laboratory, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan Department of Microbiology, Kyoto University Graduate of Medicine, Kyoto, Japan Professor emeritus, Nagasaki Uni...
متن کاملConserved OprF as a Selective Immunogen Against Pseudomonas aeruginosa
Background & Objectives: Due to the importance of Pseudomonas aeruginosa in severe inpatient infections and high mortality, the need for an efficient vaccine against these bacteria is increasing. In this regard, the general outer membrane porin of the most problematic microorganism P. aeruginosa, outer membrane protein F (OprF), is a good vaccine cand...
متن کاملα1-antitrypsin promotes SPLUNC1-mediated lung defense against Pseudomonas aeruginosa infection in mice
BACKGROUND Pseudomonas aeruginosa (PA) infection is involved in various lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. However, treatment of PA infection is not very effective in part due to antibiotic resistance. α1-antitrypsin (A1AT) has been shown to reduce PA infection in humans and animals, but the underlying mechanisms remain unclear. The goal of our stud...
متن کاملIntestinal Colonization with Enterococcus faecium Does Not Influence Pulmonary Defense against Pseudomonas aeruginosa in Mice
BACKGROUND Enterococci, and especially multiresistant Enterococcus faecium, are increasingly found colonizing hospitalized patients. This increased prevalence of colonization is not only associated with an increased prevalence of infections caused by enterococci, but also by infections with other nosocomial pathogens. In this study we investigated the causality of this observed relationship, by...
متن کاملRole of pulmonary alveolar macrophages in defense of the lung against Pseudomonas aeruginosa.
Alveolar macrophages (AM) provide one of the first lines of defense against microbial invasion in the lower airways. The role of AM in the clearance of Pseudomonas aeruginosa in mice after intrapulmonary challenge was evaluated. AM were depleted by intranasal administration of liposome-encapsulated dichloromethylene diphosphonate. At 24 h following the instillation of liposomes, a sublethal dos...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 2017
ISSN: 0950-382X
DOI: 10.1111/mmi.13768