PS216. Zizimin1 Overexpression Impairs Vascular Morphogenesis
نویسندگان
چکیده
منابع مشابه
Cell signalling during vascular morphogenesis.
Vascular tissue in plants is unique due to its diverse and dynamic cellular patterns. Through research in several organisms, such as Arabidopsis, Populus and Zinnia, using biochemical, genetic and genomic approaches, significant progress has recently been made in revealing the molecular nature of several signals underlying the patterning of vascular tissue. These signals include ligands, recept...
متن کاملSignaling vascular morphogenesis and maintenance.
Blood vessels are constructed by two processes: vasculogenesis, whereby a primitive vascular network is established during embryogenesis from multipotential mesenchymal progenitors, and angiogenesis, in which preexisting vessels (both in embryo and adult) send out capillary sprouts to produce new vessels (1-3). Endothelial cells are centrally involved in each process: They migrate and prolifera...
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Dictyostelium myoB, a member of the myosin I family of motor proteins, is important for controlling the formation and retraction of membrane projections by the cell's actin cortex (Novak, K.D., M.D. Peterson, M.C. Reedy, and M.A. Titus. 1995. J. Cell Biol. 131:1205-1221). Mutants that express a three- to sevenfold excess of myoB (myoB+ cells) were generated to further analyze the role of myosin...
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The contact site A (csA) glycoprotein is a strictly developmentally regulated plasma membrane component responsible for the EDTA-stable (Ca(2+)-independent) form of intercellular adhesion in Dictyostelium discoideum. Using inverse polymerase chain reaction and a terminator vector we have isolated a 1.6 kb genomic fragment carrying a 1.1 kb upstream region of the csA gene. This fragment had prom...
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Parathyroid hormone-related protein (PTHrP) was originally discovered as the tumor product that causes humoral hypercalcemia of malignancy. PTHrP is now known to be widely expressed in many normal fetal tissues where it may participate in the regulation of organogenesis. In this report, we document that overexpression of PTHrP in myoepithelial cells in the mammary glands of transgenic mice resu...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2014
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2014.03.190