Prunella vulgaris L. seeds: a promising source of lipids, proteins, and original phenolic compounds presenting high antioxidant and anti-inflammatory activity

Description of the subject. Prunella vulgaris L. (Lamiaceae) is an edible herb used in Europe and Asia as herbal tea, food, dietary supplement or medicinal plant since several centuries. Although composition properties aerial parts are well documented literature, seeds have never been investigated. Objectives. The aim this work was to characterize these assess not only their nutritional potential (protein, lipid minerals content), but also antioxidant anti-inflammatory specialized metabolites composition. Method. protein, lipids mineral content were determined. phenolic compounds isolated; elucidation structures done by means HR-MS one- two-dimensional NMR analysis. They then evaluated for biological activity, together with seed extracts. Results. Omega-3 rich oil interesting amino acids profile detected presence a high polyphenolic compounds, including two structurally new (phenylpropane derivatives) which isolated characterized. described here first time, named amolsamic A&B. showed potential, strong activity on neutrophils, MPO HRP models. Conclusions. These findings highlight real health promoting P. make them good candidate super-food food supplement.