PRP8 intein in dermatophytes: Evolution and species identification
نویسندگان
چکیده
منابع مشابه
PRP8 intein in cryptic species of Histoplasma capsulatum: evolution and phylogeny.
The PRP8 intein is the most widespread intein among the Kingdom Fungi. This genetic element occurs within the prp8 gene, and is transcribed and translated simultaneously with the gene. After translation, the intein excises itself from the Prp8 protein by an autocatalytic splicing reaction, subsequently joining the N and C terminals of the host protein, which retains its functional conformation....
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Classical identification of dermatophytes relies on morphological and physiological characteristics. The search for these characteristics often makes their identification long and laborious. In addition, phenotypic features can frequently vary from strain to strain or the organism can become devoid of distinguishing features. In the last few years, genotypic approaches to identification have pr...
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Inteins are selfish DNA elements found within coding regions. They are translated with their host protein, but then catalyze their own excision and the formation of a peptide bond between their flanking protein regions. Understanding what drives and selects inteins is relevant for assessing whether they have unidentified biological functions and whether they can invade and become established in...
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The phenotype of dermatophytes has been radically influenced by two very different evolutionary paths: that of the mostly sexual, soil-associated species, and that of the mostly asexual, non-soil-associated species. The former category, including geophiles and some zoophiles, is characterized by well established conidial dimorphism and the presence of apparent anti-arthropod-grazing structures ...
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Species of dermatophytes are classified into three anamorphic (asexual) genera, Epidermophyton, Microsporum, and Trichophyton. Conventional methods used to identify dermatophytes are often lengthy and may be inconclusive because of atypical microscopic or colony morphology. Based on the internal transcribed spacer 1 (ITS-1) and ITS-2 sequences of the rRNA genes, an oligonucleotide array was dev...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2017
ISSN: 1369-3786,1460-2709
DOI: 10.1093/mmy/myx102