Protolytic equlibria of bromazepam
نویسندگان
چکیده
منابع مشابه
Megadose bromazepam dependence.
BACKGROUND Benzodiazepines (BZDs) are among the most widely prescribed drugs in developed countries. Since BZDs can produce tolerance and dependence even in a short time, their use is recommended for a very limited time. However, these recommendations have been largely disregarded. The chronic use of BZDs causes a number of serious side effects, i.e. cognitive impairment, falls, traffic acciden...
متن کاملDegradation of bromazepam by the intestinal microflora.
Degradation of four benzodiazepines, i.e. bromazepam, diazepam, desmethyldiazepam, and 7bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2(1H )-one, in a broth containing human feces was studied. Degradation of bromazepam was also investigated in a fecal medium, a homogenate of the liver and a homogenate of intestinal epithelial cells of rat. More than 80% of bromazepam, which contains a pyridin...
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Methylxylenol blue or S^'-bis-Z^jiV'-diicarboxymethylJaminomethyl-^-xylenolsulfonephthalein belongs to the group of metallochromic indicators prepared by Körbt and Přibil [1] via condensation of common sulfonephthalein dyes with formaldehyde and iminodiacetic acid. Recently it has been newly prepared by Cherkesov and co-workers [2] and named ^-xylenolphthalexon S. Two indicators from this group...
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Fluorescein is one of most used fluorescent labels for characterizing biological systems, such as proteins, and is used in fluorescence microscopy. However, if fluorescein is to be used for quantitative measurements involving proteins then one must account for the fact that the fluorescence of fluorescein-labeled protein can be affected by the presence of intrinsic amino acids residues, such as...
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ژورنال
عنوان ژورنال: Journal of the Serbian Chemical Society
سال: 2002
ISSN: 0352-5139,1820-7421
DOI: 10.2298/jsc0203187p