Proteomic profiling of the infective trophozoite stage of Acanthamoeba polyphaga
نویسندگان
چکیده
منابع مشابه
Survival of environmental mycobacteria in Acanthamoeba polyphaga.
Free-living amoebae in water are hosts to many bacterial species living in such an environment. Such an association enables bacteria to select virulence factors and survive in adverse conditions. Waterborne mycobacteria (WBM) are important sources of community- and hospital-acquired outbreaks of nontuberculosis mycobacterial infections. However, the interactions between WBM and free-living amoe...
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BACKGROUND Mycobacterium smegmatis is a rapidly-growing mycobacterium causing rare opportunistic infections in human patients. It is present in soil and water environments where free-living amoeba also reside, but data regarding M. smegmatis-amoeba relationships have been contradictory from mycobacteria destruction to mycobacteria survival. METHODOLOGY/PRINCIPAL FINDINGS Using optic and elect...
متن کاملEnhanced growth of surface-attached Acanthamoeba polyphaga.
Acanthamoeba keratitis remains a problematic infection, especially for contact lens wearers. Current treatment is not always effective, and Acanthamoeba spp. may persist on contact lenses despite the use of disinfectant. Growth of Acanthamoeba polyphaga in culture medium without bacteria has already been studied (3), but we know of no previous studies of the effect of surface attachment on this...
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Acanthamoeba polyphaga mimivirus is a member of the giant nucleocytoplasmic large DNA viruses, infecting various Acanthamoeba spp. The genomes of giant viruses encode components previously thought to be exclusive to cellular life, such as proteins involved in nucleic acid and protein synthesis. Recent work on enzymes involved in carbohydrate biosynthesis and metabolism show that instead of util...
متن کاملGene&Genome Duplication in Acanthamoeba Polyphaga Mimivirus
Gene duplication is key to molecular evolution in all three domains of life and may be the first step in the emergence of new gene function. It is a well recognized feature in large DNA viruses, but has not been studied extensively in the largest known virus to date, the recently discovered Acanthamoeba Polyphaga Mimivirus. Here we present a systematic analysis of gene and genome duplication ev...
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ژورنال
عنوان ژورنال: Acta Tropica
سال: 2014
ISSN: 0001-706X
DOI: 10.1016/j.actatropica.2014.08.009