منابع مشابه
Proteomic Findings in Melanoma.
Although the emergence of proteomics as an independent branch of science is fairly recent, within a short period of time it has contributed substantially in various disciplines. The tool of mass spectrometry has become indispensable in the analysis of complex biological samples. Clinical applications of proteomics include detection of predictive and diagnostic markers, understanding mechanism o...
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Functional proteomics provides a powerful approach to screen for alterations in protein expression and posttranslational modifications under conditions of human disease. In this study, we use protein screening to examine markers of melanoma progression, by profiling melanocyte versus melanoma cell lines using two-dimensional electrophoresis and mass spectrometry. Eight candidate markers were id...
متن کاملDermatoscopic Findings of Seborrheic Keratosis in Melanoma.
Cutaneous melanoma may in some instances be confused with seborrheic keratosis, which is a very common neoplasia, more often mistaken for actinic keratosis and verruca vulgaris. Melanoma may clinically resemble seborrheic keratosis and should be considered as its possible clinical simulator. We report a case of melanoma with dermatoscopic characteristics of seborrheic keratosis and emphasize th...
متن کاملThoracoscopic findings of malignant melanoma.
A 38-year-old male presented to our hospital with the chief complaint of chronic cough. Eight years previously he was diagnosed with cilioretinal malignant melanoma and underwent left ophthalmectomy. On chest CT, pleural effusion and diffuse thickening of left pleura were suspected (Picture 1). The differential diagnosis included mesothlioma and metastatic melanoma. In thoracoscopic findings mu...
متن کاملIn-depth proteomic profiling of the uveal melanoma secretome
Uveal melanoma (UM), the most common primary intraocular tumour in adults, is characterised by a high frequency of metastases to the liver, typically with a fatal outcome. Proteins secreted from cancer cells ('secretome') are biologically important molecules thought to contribute to tumour progression. We examined the UM secretome by applying a label-free nanoLCMS/MS proteomic approach to profi...
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ژورنال
عنوان ژورنال: Journal of Proteomics & Bioinformatics
سال: 2016
ISSN: 0974-276X
DOI: 10.4172/jpb.1000e29