Proteolysis, Fibrinolysis, and Coagulation

Proteolysis, fibrinolysis, and coagulation. Significance in thrombolytic therapy.

Coagulation and fibrinolysis after injury.

Blood coagulation, fibrinolysis and exercise.

Fibrinolysis and proteolysis in a cellular context.

In this issue of Thrombosis and Haemostasis a collection of review articles and original contributions have been published coinciding with the “17th International Congress on Fibrinolysis and Proteolysis” to be held in Melbourne, Australia, at the end of March 2004. It is widely acknowledged that the field of fibrinolysis and proteolysis has enormously expanded since the early discoveries of, f...

Blood Coagulation, Fibrinolysis and Cellular Haemostasis Introduction

A high plasma concentration of coagulation factor VIII (FVIII) is an important risk factor for venous thromboembolism (VTE) (1-4). In the Leiden Thrombophilia study for example, FVIII levels above 1500 IU/L conferred an almost 5-fold risk for a first episode of deep-vein thrombosis (1). Most importantly, high FVIII is also associated with a very high risk of recurrent venous thromboembolism (4,...