Proteoglycans in Leiomyoma and Normal Myometrium
نویسندگان
چکیده
منابع مشابه
Galactosaminoglycans from normal myometrium and leiomyoma.
In many tumors, the amount of chondroitin sulfate in the extracellular matrix has been shown to be elevated when compared to the corresponding normal tissue. Nevertheless, the degree of chondroitin sulfate increase varies widely. In order to investigate a possible correlation between the amount of chondroitin sulfate and tumor size, several individual specimens of human leiomyoma, a benign uter...
متن کاملEstrogen receptors (ERa/ERb) in normal and pathological growth of the human myometrium: pregnancy and leiomyoma
Benassayag, C., M. J. Leroy, V. Rigourd, B. Robert, J. C. Honoré, T. M. Mignot, M. C. Vacher-Lavenu, C. Chapron, and F. Ferré. Estrogen receptors (ERa/ERb) in normal and pathological growth of the human myometrium: pregnancy and leiomyoma. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E1112–E1118, 1999.—The distributions of the mRNAs for estrogen receptors (ERa and ERb) and their binding propert...
متن کاملEstrogen receptors (ERα/ERβ) in normal and pathological growth of the human myometrium: pregnancy and leiomyoma.
The distributions of the mRNAs for estrogen receptors (ERα and ERβ) and their binding properties in myometria of pregnant and nonpregnant women and in leiomyoma were studied. RT-PCR analysis indicated that the term pregnancy myometria had little ERα mRNA, whereas the amounts of ERβ mRNAs in pregnant or nonpregnant myometria appeared to be similar. Both ERα and ERβ mRNA were greater in certain l...
متن کاملTenascin-X and leukemia inhibitory factor receptor are down-regulated in leiomyoma compared with normal myometrium.
OBJECTIVE Uterine leiomyomas are the most common tumor of the uterus. But the molecular causes of uterine leiomyoma remain unclear. We conducted the current investigation in order to elucidate the molecular mechanisms in the development of uterine leiomyoma. METHODS We employed a new and accurate reverse transcription-polymerase chain reaction (RT-PCR) method that involved annealing control p...
متن کاملVariants of Leiomyoma: Histomorphological Study of Tumors of Myometrium
Objectives: To study the histomorphological features of variants of leiomyomas of myometrium in our institution from hysterectomy and myomectomy specimens. Methods: In this prospective study, 1,845 hysterectomy and myomectomy specimens collected over a period of two years were studied. A detailed gross and microscopic examination of tumors of myometrium were made after fixing and staining the s...
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ژورنال
عنوان ژورنال: Reproductive Sciences
سال: 2015
ISSN: 1933-7191,1933-7205
DOI: 10.1177/1933719115607994