Proteoglycans, glycosaminoglycans and sulfated polysaccharides from connective tissues
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چکیده
منابع مشابه
Glycosaminoglycans and Proteoglycans
In this editorial to MDPI Pharmaceuticals special issue "Glycosaminoglycans and Proteoglycans" we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan, serglycin, cell-surface proteoglycans, like syndecans and glypicans, and the extracellular matrix proteoglycans, like aggrecan, perlecan, and ...
متن کاملSulfated glycosaminoglycans from ovary of Rhodnius prolixus.
We have characterized sulfated glycosaminoglycans from ovaries of the blood-sucking insect Rhodnius prolixus, and determined parameters of their synthesis and distribution within this organ by biochemical and histochemical procedures. The major sulfated glycosaminoglycan is heparan sulfate while chondroitin 4-sulfate is a minor component. These glycosaminoglycans are concentrated in the ovarian...
متن کاملGlycosaminoglycans and proteoglycans: overlooked entities?
BACKGROUND By virtue of their high net negative charge, glycosaminoglycans and proteoglycans play pivotal roles in biologic processes such as cell-cell and cell-matrix interactions, sequestration of growth factors, activation of chemokines and cytokines, and permselectivity of basement membranes. METHODS The present article reviews the putative roles of glycosaminoglycans and proteoglycans in...
متن کاملSulfated polysaccharides fucoidans from brown algae
The immunotropic activity of structurally different fucoidans and their derivatives towards isolated immune blood cells, effectors of innate immune system, was studied. The most potent effect was observed for high molecular weight fucoidan CF from the alga Chordaria flagelliformis, whose backbone is built of (1→3)-linked units of α-L-fucopyranose, and branches included residues of α-D-glucuroni...
متن کامل[Neuroprotective effects of sulfated polysaccharides from seaweed].
Currently, neurodegenerative diseases (NDD) occupy a significant place in the structure of disease of the elderly, which dictates the need to find new and effective treatment and prevention of this pathology. At the heart of NDD development is a violation of the metabolism and the conformational change of cellular proteins with subsequent accumulation and aggregation of their in certain groups ...
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ژورنال
عنوان ژورنال: Memórias do Instituto Oswaldo Cruz
سال: 1991
ISSN: 0074-0276
DOI: 10.1590/s0074-02761991000700003