Protein synthesis: Imprinting through molecular mimicry

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Protein synthesis: Imprinting through molecular mimicry

The translation of genetic messages into proteins on ribosomes is catalyzed by a number of proteins that bind transiently to the ribosome [1,2]. These are the initiation, elongation and release (termination) factors. Several of these factors are GTP-hydrolyzing (G) proteins, which undergo a conformation transition between an active state with bound GTP and an inactive state with bound GDP. In b...

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A new strategy of molecular imprinting to prepare spherical hydrogels via water-in-oil Pickering emulsion polymerization was developed. The imprinted hydrogels exhibited fast adsorption kinetics and significant selectivity for the target protein.

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EditoriAL EditoriAL Over the course of evolution, microorganisms have developed innovative survival strategies to thrive in their hosts. 1 The human body is home to many species of bacteria, viruses, fungi, and other invertebrate parasites. Some of these organisms that live and thrive in humans are com-mensals and are harmless. They may be also beneficial to the host as they provide certain nut...

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Molecular mimicry: histone H3 and mycobacterial protein epitopes.

A 15-kDa protein detected initially in amyloidotic ileum from a transgenic mouse and subsequently in control (nontransgenic) ileum by various polyclonal rabbit antiserums applied to electroblots of extracts derived from these tissues was identified by partial sequence analysis as histone H3. Antiserums were made against immunogens unrelated to the histone, but they recognized calf thymus histon...

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ژورنال

عنوان ژورنال: Current Biology

سال: 1996

ISSN: 0960-9822

DOI: 10.1016/s0960-9822(02)00469-4