Protein surface charge of trypsinogen changes its activation pattern
نویسندگان
چکیده
منابع مشابه
Protein surface charge of trypsinogen changes its activation pattern
BACKGROUND Trypsinogen is the inactive precursor of trypsin, a serine protease that cleaves proteins and peptides after arginine and lysine residues. In this study, human trypsinogen was used as a model protein to study the influence of electrostatic forces on protein-protein interactions. Trypsinogen is active only after its eight-amino-acid-long activation peptide has been cleaved off by anot...
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ژورنال
عنوان ژورنال: BMC Biotechnology
سال: 2014
ISSN: 1472-6750
DOI: 10.1186/s12896-014-0109-5