Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network
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چکیده
منابع مشابه
Protein Kinase D Regulates the Fission of Cell Surface Destined Transport Carriers from the Trans-Golgi Network
When a kinase inactive form of Protein Kinase D (PKD-K618N) was expressed in HeLa cells, it localized to the trans-Golgi network (TGN) and caused extensive tubulation. Cargo that was destined for the plasma membrane was found in PKD-K618N-containing tubes but the tubes did not detach from the TGN. As a result, the transfer of cargo from TGN to the plasma membrane was inhibited. We have also dem...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2004
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb1090