Protein flexibility in docking and surface mapping
نویسندگان
چکیده
منابع مشابه
Protein-protein docking with backbone flexibility.
Computational protein-protein docking methods currently can create models with atomic accuracy for protein complexes provided that the conformational changes upon association are restricted to the side chains. However, it remains very challenging to account for backbone conformational changes during docking, and most current methods inherently keep monomer backbones rigid for algorithmic simpli...
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Acknowledgements I would like to start by thanking Prof. Meir Edelman and Dr. Vladimir Sobolev for their guidance and the high level of scientific independence they trusted in me. A different posture would not have permitted my full development as a free thinker. I would like to thank Professors Ron Unger and Amnon Horovitz for their valuable comments throughout this work as assigned readers of...
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ژورنال
عنوان ژورنال: Quarterly Reviews of Biophysics
سال: 2012
ISSN: 0033-5835,1469-8994
DOI: 10.1017/s0033583512000066