Protein-DNA interactions in the epsilon-globin gene silencer.
نویسندگان
چکیده
منابع مشابه
Alterations in protein-DNA interactions in the gamma-globin gene promoter in response to butyrate therapy.
The mechanisms by which pharmacologic agents stimulate gamma-globin gene expression in beta-globin disorders has not been fully established at the molecular level. In studies described here, nucleated erythroblasts were isolated from patients with beta-globin disorders before and with butyrate therapy, and globin biosynthesis, mRNA, and protein-DNA interactions were examined. Expression of gamm...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1993
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)53712-1