Protein Binding of Semisynthetic Penicillins
نویسندگان
چکیده
منابع مشابه
Significance of Protein Binding of Penicillins
A large volume of data on variations in serum penicillin levels has been obtained from work carried out with depot preparations of procaine benzyl penicillin in oil (to be published). Figure 1 shows frequency histograms of blood levels obtained in humans 24 hours after a single fixed dose of the same preparation. Large groups of individuals were involved and there was an interesting difference ...
متن کاملEffect of semisynthetic penicillins on the Limulus lysate test.
Semisynthetic penicillins in concentrations greater than 1.0% (wt/vol) were found to inhibit the limulus lysate assay for endotoxin.
متن کاملComparative in vitro activity of semisynthetic penicillins against Proteeae.
The in vitro susceptibilities of 181 isolates of precisely identified Proteeae species to five semisynthetic penicillins were determined with low and high inocula. Significant differences in susceptibility patterns among various Proteeae species to the penicillins examined were demonstrated. Providencia stuartii was clearly distinguished from Providencia alcalifaciens by its greater resistance ...
متن کاملIn vitro microbiological evaluation of TEI-1194 and TEI-2012, novel antipseudomonal semisynthetic penicillins.
TEI-1194, sodium 6-[D-(-)-alpha-(coumarin-3-carboxamide)-phenylacetamide] penicillanate and TEI-2012, sodium 6[D-(-)alpha-(8-hydroxy-coumarin-3-carboxamide)-phenylacetamide] penicillanate are new semisynthetic penicillin derivatives both possessing a broad spectrum of in vitro antibacterial activities. Minimal inhibitory concentrations of both agents were compared with carbenicillin. TEI-1194 a...
متن کاملTicarcillin, carbenicillin and BL-P1908. In vitro comparison of three anti-pseudomonal semisynthetic penicillins.
Ticarcillin, carbenicillin and BL-P1908, a new anti-pseudomonal semisynthetic penicillin, were subjected to several in vitro comparisons-including minimal inhibitory and lethal concentrations (MIC and MLC), effects of inoculum size, effects of buffering the media and regression analyses of MIC and disc diffusion data. Whereas ticarcillin and carbenicillin showed comparable spectra of activity, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1964
ISSN: 0032-5473
DOI: 10.1136/pgmj.40.suppl.23